ABSTRACT
Background: Severe Acute Respiratory Syndrome Corona Virus 2(SARS?CoV?2) is the novel corona virus first detected in Wuhan in 2019. nCOV belongs to the ?-corona virus cluster. As the third most highly pathogenic corona virus, the clinical presentations of 2019-nCoV infection resemble those of the other two corona viruses, Severe Acute Respiratory Syndrome Corona Virus (SARS-CoV) and Middle East Respiratory Syndrome Corona Virus (MERS-CoV). The abnormalities in the laboratory indices particularly the Blood Biochemical parameters may be associated with the severity of multiple organ dysfunction seen in COVID-19. The aim of the present project was to analyze the laboratory diagnostic profile of sars?cov?2 (covid?19) patients & to study the associated factors.Methods: The present hospital � based cross sectional study was conducted on all the patients who had tested positive for COVID & were admitted in Rajindra Hospital, Patiala in the time period of the July 2020 to December 2020, during the declared Corona Virus Pandemic. All the Biochemical Parameters were estimated on the automatic Analysers.Results: The results of the present study show abnormalities in the Renal Function Tests, Liver Function Tests, Blood sugar levels and Serum Electrolytes. Blood sugar levels and Renal function tests are significantly deranged in the patients of Covid 19 having co-morbidities like Diabetes Mellitus, Hypertension, CAD, CKD, Hypothyroidism etc: Conclusions:Biochemical Laboratory parameters
ABSTRACT
The falcine sinus is an intrauterine anatomic structure located in the falx cerebri that is closed after birth and persistenceof this embryologic falcine sinus is considered as a rare variation of the venous pathway which is associated with defect in the development of the straight sinus leading to formation of an alternate venous pathway served by the persistent falcine sinus. Cranium bifidum occultum is another rare skull ossification disorder referred to as the Catlin mark characterized by ossification defects in the parietal bones. Many other associated anomalies can be seen with persistent falcine sinus apart from cranium bifidum occultum which include absent or dysplastic tentorium cerebelli, agenesis of the corpus callosum, apert syndrome, atretic occipital/parietal encephalocele, vein of galen malformation, osteogenesis imperfecta, and chiari malformation Type II. We describe a rare case of a 10-year-old girl who presented with short stature, intermittent headache, and abnormal skull shape. On radiological examination, persistent falcine sinus was detected with large midline skull defect at the high parietal area. The straight sinus was absent, and there was dysplastic tentorium cerebelli. In addition to these, craniosynostosis was also present with many other associated anomalies. Persistent falcine sinus and cranium bifidum occultum are very rare, and when found, they are associated with many anomalies raising the possibility that they may represent the benign end of the same developmental spectrum. To the best of our knowledge, these constellations of anomalies have been reported in very few children.